Ipamorelin is a pentapeptide GH secretagogue and ghrelin receptor agonist. It is highly selective for GH release u2014 unlike GHRP-2 or GHRP-6, it does not significantly elevate cortisol, aldosterone, or prolactin at standard doses. Best administered pre-bed to coincide with natural GH secretion.
Overview
Reconstitution Table (2 mL mL BAC water u2192 2 mg)
| Phase | Dose | Draw (U-100) |
| Starting dose | 100 mcg | 1 Unit |
| Standard dose | 200u2013300 mcg | 2u20133 Units |
Reconstitute 2 mg with 2 mL BAC water u2192 1,000 mcg/mL. Inject SC 30u201360 min before sleep. Avoid carbohydrates 2 hours before injection (blunts GH pulse).
Ipamorelin does not cause cortisol spikes typical of older GHRPs. Still, extended use should be cycled (e.g. 12 weeks on, 4 weeks off). Research use only.
Potential Benefits & Side Effects
Potential Benefits
- Clean GH pulse without cortisol elevation
- Improved sleep quality and recovery
- Lean body mass support
- Bone density maintenance
- Anti-aging potential through IGF-1 axis
Possible Side Effects
- Water retention at higher doses
- Mild headache (initial use)
- Mild injection-site redness
Storage Instructions
Lyophilized Powder
- Short-term (<3 months): Refrigerate at 2u00b0Cu20138u00b0C
- Long-term: Freeze at u221220u00b0C or lower
- Protect from light and moisture
- Allow vial to reach room temperature before opening
Reconstituted Solution
- Refrigerate at 2u00b0Cu20138u00b0C u2014 do not freeze
- Use within 28 days when reconstituted with BAC water
- Always use sterile technique when drawing doses
References
Raun K. et al. (1998)
Ipamorelin u2014 a new GH-releasing peptide with no effect on motilin
View SourceImportant Note
This protocol guide is for educational and research purposes only. It is not medical advice. Always consult a qualified healthcare professional before using any peptide compound.