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CJC-1295 (Mod-GRF 1-29) Protocol

Published August 27, 2026 1 min read 2 mg Peer-Reviewed

Overview

CJC-1295 without DAC (Modified GRF 1-29) is a 29-amino acid GHRH analogue with a short half-life (~30 min). Unlike the DAC version, it does not produce sustained GH elevation u2014 it amplifies a single natural pulse when co-administered with a GHRP like Ipamorelin. This combination is often described as the gold standard for physiological GH optimisation.

Dosing & Reconstitution Guide

Once daily (pre-bed) u00b7 100 mcg u00b7 Half-life: ~30 min

Reconstitution Table (2 mL mL BAC water u2192 2 mg)

Compound Dose Draw (U-100)
CJC-1295 no DAC 100 mcg 1 Unit
Combined with Ipamorelin 200u2013300 mcg Ipa + 100 mcg CJC Draw in same syringe

Reconstitute 2 mg with 2 mL BAC water u2192 1,000 mcg/mL. Can be combined in the same syringe with Ipamorelin. Administer 30u201360 min pre-bed.

Do not confuse with CJC-1295 with DAC (much longer half-life, different dosing schedule). Research use only.

Potential Benefits & Side Effects

Potential Benefits

  • Synergistic GH pulse with GHRP combination
  • Improved sleep architecture
  • Body composition support
  • Preserves pituitary signalling (vs exogenous HGH)

Possible Side Effects

  • Water retention
  • Headache (mild)
  • Transient flushing

Storage Instructions

Lyophilized Powder

  • Short-term (<3 months): Refrigerate at 2u00b0Cu20138u00b0C
  • Long-term: Freeze at u221220u00b0C or lower
  • Protect from light and moisture
  • Allow vial to reach room temperature before opening

Reconstituted Solution

  • Refrigerate at 2u00b0Cu20138u00b0C u2014 do not freeze
  • Use within 28 days when reconstituted with BAC water
  • Always use sterile technique when drawing doses

References

Ionescu M. et al. (2004)

Sustained supraphysiologic levels of GH after CJC-1295 administration

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Important Note

This protocol guide is for educational and research purposes only. It is not medical advice. Always consult a qualified healthcare professional before using any peptide compound.