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GHK-Cu Skin Repair Protocol

Published August 27, 2026 1 min read 200 mg Popular

Overview

GHK-Cu is a naturally occurring copper peptide first isolated from human plasma. Levels decline significantly with age. It stimulates collagen, elastin, and glycosaminoglycan synthesis and modulates over 4,000 genes u2014 resetting aged expression patterns toward a more youthful profile.

Dosing & Reconstitution Guide

Once or twice daily u00b7 1u20132 mg/mL topical u00b7 Half-life: Short (topical)

Reconstitution Table (N/A (topical) mL BAC water u2192 200 mg)

Application Concentration Frequency
Anti-aging skin 0.1u20130.5% Once daily
Wound healing 1u20132% Twice daily
Hair loss (scalp) 0.5u20131% Once daily

For topical use: dissolve in a lotion or serum base. For injection: dissolve in sterile saline. Store reconstituted solution at 2u20138u00b0C and use within 14 days.

GHK-Cu is generally well-tolerated topically. Avoid eye contact. Systemic injection use is experimental. Research use only.

Potential Benefits & Side Effects

Potential Benefits

  • Skin firmness and wrinkle reduction
  • Wound healing acceleration
  • Hair follicle stimulation
  • Anti-inflammatory gene modulation
  • UV damage repair

Possible Side Effects

  • Temporary skin discolouration (high concentrations)
  • Contact irritation (rare)
  • Mild blue tint at application site (copper u2014 harmless)

Storage Instructions

Lyophilized Powder

  • Short-term (<3 months): Refrigerate at 2u00b0Cu20138u00b0C
  • Long-term: Freeze at u221220u00b0C or lower
  • Protect from light and moisture
  • Allow vial to reach room temperature before opening

Reconstituted Solution

  • Refrigerate at 2u00b0Cu20138u00b0C u2014 do not freeze
  • Use within 28 days when reconstituted with BAC water
  • Always use sterile technique when drawing doses

References

Pickart L. et al. (2015)

The human tripeptide GHK-Cu in prevention of oxidative stress

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Important Note

This protocol guide is for educational and research purposes only. It is not medical advice. Always consult a qualified healthcare professional before using any peptide compound.