Selank and Semax operate on complementary pathways. Selank modulates serotonin transport and enkephalinase activity, producing anxiolysis without sedation. Semax drives BDNF and NGF upregulation, enhancing neuroplasticity. The combination creates an anxiolytic-nootropic profile supporting both stress performance and baseline cognitive function.
Overview
Reconstitution Table (2 mL + 10 mL mL BAC water u2192 5 mg + 30 mg)
| Compound | Dose | Route |
| Selank | 250 mcg | Intranasal or SC |
| Semax | 200u2013400 mcg | Intranasal (preferred) |
Administer Semax first (morning, intranasal). Follow with Selank 1u20132 hours later or simultaneously for anxiety control. Both can be administered intranasally using diluted solutions.
Do not take Semax within 4 hours of sleep. Both peptides are approved in Russia. Research use only outside Russia/CIS.
Potential Benefits & Side Effects
Potential Benefits
- Anxiety reduction without sedation
- BDNF/NGF upregulation
- Working memory and focus enhancement
- Stress resilience improvement
- Immunomodulatory effects (Selank)
Possible Side Effects
- Insomnia if Semax taken late (Semax)
- Nasal irritation
- Fatigue at high Selank doses
Storage Instructions
Lyophilized Powder
- Short-term (<3 months): Refrigerate at 2u00b0Cu20138u00b0C
- Long-term: Freeze at u221220u00b0C or lower
- Protect from light and moisture
- Allow vial to reach room temperature before opening
Reconstituted Solution
- Refrigerate at 2u00b0Cu20138u00b0C u2014 do not freeze
- Use within 28 days when reconstituted with BAC water
- Always use sterile technique when drawing doses
References
Important Note
This protocol guide is for educational and research purposes only. It is not medical advice. Always consult a qualified healthcare professional before using any peptide compound.